Status:

COMPLETED

Delayed Cord Clamping for Congenital Diaphragmatic Hernia

Lead Sponsor:

Children's Hospital of Philadelphia

Collaborating Sponsors:

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Conditions:

Congenital Diaphragmatic Hernia

Eligibility:

All Genders

1-1 years

Phase:

NA

Brief Summary

Congenital diaphragmatic hernia (CDH) is a congenital anomaly associated with a high risk of mortality and need for life-saving interventions such as extracorporeal membrane oxygenation (ECMO), nitric...

Detailed Description

Congenital diaphragmatic hernia (CDH) is a congenital anomaly associated with a high risk of mortality (29%) and need for life-saving interventions such as ECMO (33%), nitric oxide (62%), and vasopres...

Eligibility Criteria

Inclusion

  • Antenatal diagnosis of CDH, with care in the Center for Fetal Treatment
  • Gestational age ≥ 36 weeks at birth

Exclusion

  • Multiple gestation
  • Major anomalies or aneuploidy
  • Enrolled in fetal endoluminal tracheal occlusion (FETO) trial
  • Palliative care planned or considered
  • Maternal diagnosis placenta previa, accreta, or abruption
  • Maternal diagnosis pre-eclampsia requiring Magnesium sulfate therapy at time of delivery
  • Obstetrics (OB) or Neonatal provider concerns for the clinical care of the mother or infant, or study team not available

Key Trial Info

Start Date :

October 12 2017

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 9 2018

Estimated Enrollment :

21 Patients enrolled

Trial Details

Trial ID

NCT03314233

Start Date

October 12 2017

End Date

October 9 2018

Last Update

January 21 2020

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Children's Hospital of Philadelphia

Philadelphia, Pennsylvania, United States, 19104