Status:
UNKNOWN
The Efficacy of Hepatectomy or TILA-TACE in Patients With Resectable Hepatocellular Carcinoma
Lead Sponsor:
Second Affiliated Hospital, School of Medicine, Zhejiang University
Conditions:
Surgical Resection
HCC
Eligibility:
All Genders
18-75 years
Phase:
NA
Brief Summary
Hepatocellular carcinoma (HCC) is one of the most common cancers in the world with major occurrences in eastern Asian countries such as China. HCC is the third leading cause of cancer-related deaths i...
Detailed Description
The Barcelona Clinic Liver Cancer staging system (BCLC) is one of the more recognized staging criteria and has been recommended by the European Association for the Study of Liver and the American Asso...
Eligibility Criteria
Inclusion
- Ages 18-75 with no gender, ethnicity, religion, or geographical restrictions.
- Diagnosed HCC patient.
- The following criteria will be used for the evaluation of tumor resectability and adequate remaining liver volume: ≥ 30% remaining liver volume/total liver volume for non-hepatitis patients; ≥ 40% remaining liver volume/total liver volume for hepatitis patients.
- Imaging examination with no cancer embolus above the secondary branch of the portal vein.
- New lesions found five years after liver cancer treatment.
- Child-Pugh A or B grade liver function.
- No concurrent malignancies in other systems.
- Informed subjects who fully understand and willingly cooperate with the test program with signed relevant documents.
Exclusion
- Suffer from other malignancies.
- Have received any other liver cancer treatments.
- Pathological diagnosis as non-HCC.
- Experience large blood vessel invasion, distant metastases, or unresectable liver cancer.
- One or more organ failures.
- Child-Pugh C grade liver function.
- Incomplete surgical resection or TILA-TACE.
Key Trial Info
Start Date :
November 1 2017
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2022
Estimated Enrollment :
230 Patients enrolled
Trial Details
Trial ID
NCT03314532
Start Date
November 1 2017
End Date
December 31 2022
Last Update
October 19 2017
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
The Second Affiliated Hospital Zhejiang University School of Medicine
Hanzhou, Zhejiang, China, 310009