Status:

COMPLETED

Phase 3 Safety and Immunogenicity Study of aQIV in Elderly Adults

Lead Sponsor:

Seqirus

Conditions:

Influenza, Human

Eligibility:

All Genders

65+ years

Phase:

PHASE3

Brief Summary

This phase 3 study is a randomized, double-blinded, comparator controlled, parallel-group, multicenter study of aQIV versus the US-licensed 2017-2018 adjuvanted trivalent influenza vaccine (aTIV-1, Fl...

Eligibility Criteria

Inclusion

  • Males and females ≥ 65 years old who are healthy or have co-morbidities
  • Individuals who or whose legal representative(s) have voluntarily given written consent after the nature of the study has been explained according to local regulatory requirements, prior to study entry
  • Ability to attend all scheduled visits and to comply with study procedures including diary card completion and follow-up

Exclusion

  • History of behavioral or cognitive impairment or psychiatric condition
  • Hypersensitivity, including allergy, to any component of vaccines, medicinal products or medical equipment whose use is foreseen in this study
  • Abnormal function of the immune system
  • Receipt of any influenza vaccine within 6 months prior to enrollment in this study, or plan to receive influenza vaccine prior to the Day 22 blood collection
  • Any other clinical condition that, in the opinion of the Investigator, might interfere with the results of the study or pose additional risk to the subject due to participation in the study
  • Additional eligibility criteria may be discussed by contacting the site.

Key Trial Info

Start Date :

October 17 2017

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 17 2018

Estimated Enrollment :

1778 Patients enrolled

Trial Details

Trial ID

NCT03314662

Start Date

October 17 2017

End Date

May 17 2018

Last Update

July 22 2020

Active Locations (20)

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Page 1 of 5 (20 locations)

1

Coastal Clinical Research, Inc.

Mobile, Alabama, United States, 36608

2

Anaheim Clinical Trials

Anaheim, California, United States, 92801

3

Paradigm clinical Research Centers, Inc

Redding, California, United States, 96001

4

Clinical Research of South Florida, an AMR Company

Coral Gables, Florida, United States, 33134