Status:
UNKNOWN
Mechanical Ventilation in Multiple Fracture Ribs
Lead Sponsor:
Assiut University
Conditions:
Mechanical Ventilation
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
Chest trauma is the most common injury in the emergency trauma and rib fractures is the most common trauma in chest trauma. Severe rib fractures can cause paradoxical respiration and mediastinal swing...
Detailed Description
To compare between Biphasic Intermittent Positive Airway Pressure (BIPAP) ventilation and Airway Pressure Release Ventilation (APRV) mode in patients with multiple fracture ribs as regard: * Resting ...
Eligibility Criteria
Inclusion
- • Isolated chest trauma patient with Multiple fracture ribs patients \[ \>3 ribs\] who will be admitted to the surgical ICU for ventilatory support and will be expected to continue for 2 days or longer
Exclusion
- Age \< 18 years old.
- Pregnant patient.
- Patient who will require fraction of inspired oxygen more than 0.6.
- Air leak from the chest tube.
- Patient with body temperature \> 39 Celsius.
- Acute hepatitis or severe liver disease (Child-Pugh class C).
- Left ventricular ejection fraction less than 30%.
- Heart rate less than 50 beats/min.
- Second or third-degree heart block.
- Systolic pressure \< 90 mmHg despite of infusion of 2 vasopressors.
- Patients with known endocrine dysfunction.
- Patient with hypothermia
- Patient on Positive end expiratory pressure more than 14 cmH2o
Key Trial Info
Start Date :
October 25 2017
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2018
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT03314701
Start Date
October 25 2017
End Date
December 1 2018
Last Update
July 9 2018
Active Locations (1)
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1
Faculty of Medicine
Asyut, Egypt