Status:

COMPLETED

Age-dependent Changes in the Responsiveness of Hypothalamic Pituitary Gonadal Axis in Men

Lead Sponsor:

Quaid-e-Azam University

Conditions:

Sterility, Reproductive

Eligibility:

MALE

25-75 years

Phase:

PHASE3

Brief Summary

The present study was designed to assess the responsiveness of the hypothalamic pituitary gonadal axis to kisspeptin administration with increasing age in men.

Detailed Description

Little is known about the involvement of kisspeptin signalling in the causation of senescence-basal modulation of the GnRH-LH unit in any model and particularly in advance age men. The present study w...

Eligibility Criteria

Inclusion

  • • Age

Exclusion

  • Hepatic and renal complications
  • Epilepsy
  • Pneumonia
  • Asthma
  • Orchitis
  • Hernia
  • Cryptorchidism
  • Cardiovascular diseases
  • Reproductive disorders
  • Mental retardation

Key Trial Info

Start Date :

August 8 2014

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 5 2015

Estimated Enrollment :

15 Patients enrolled

Trial Details

Trial ID

NCT03315325

Start Date

August 8 2014

End Date

March 5 2015

Last Update

October 23 2017

Active Locations (1)

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Quaid-i-Azam University

Islamabad, Pakistan, 45320