Status:

COMPLETED

The Efficacy and Safety of Composite Steep-pulse Treatment Apparatus Used in Prostate Cancer Focal Therapy

Lead Sponsor:

Second Military Medical University

Conditions:

Prostate Cancer

Eligibility:

MALE

30-75 years

Phase:

NA

Brief Summary

This trial is studying the effects and safety in treating patients with local prostate cancer with a new IRE device called Composite Steep-pulse Treatment Apparatus. This new device could cause cell i...

Detailed Description

Background: Prostate cancer is the most common cancer in elderly males in western country. It is also a major health concern, especially in China with its greater proportion of elderly men in the gen...

Eligibility Criteria

Inclusion

  • Prostate MRI can identify the suspect region(pi-RADS≥4 ) ,and no evidence of lymphatic metastasis
  • Patients must have confirmed prostate cancer by prostate biopsy
  • There must be no evidence of metastatic disease as confirmed by ECT and whole-body MRI
  • No prostatic calculus or prostatic calculus≤5mm
  • No contraindication on total intravenous anesthesia
  • Not take any anticoagulants before or discontinue anticoagulant therapy at least 7 days
  • Age ≥ 30 - ≤ 75 years
  • Life expectancy of greater than 10 years
  • Patients scheduled for radical prostatectomy.
  • Sexually potent

Exclusion

  • Patients have previously undergone radical prostatectomy.
  • Patients have previously undergone hormonal therapy or radiotherapy.
  • Patients underwent other surgery before less than 3 months
  • Clinically significant cardiovascular disease
  • Patients with other malignant tumor or patients with hiv.
  • Uncontrolled intercurrent illness including, but not limited to, ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, or psychiatric illness/social situations that would limit compliance with study requirements
  • Patients with poor health condition
  • Simultaneous participation in another clinical trial

Key Trial Info

Start Date :

April 27 2017

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 27 2017

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT03315585

Start Date

April 27 2017

End Date

October 27 2017

Last Update

April 13 2018

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Changhai Hospital,Second Military Medical University

Shanghai, Shanghai Municipality, China, 200000