Status:
COMPLETED
Simplified Isoniazid Preventive Therapy Strategy to Reduce TB Burden
Lead Sponsor:
University of California, San Francisco
Collaborating Sponsors:
Makerere University
National Institute of Allergy and Infectious Diseases (NIAID)
Conditions:
Tuberculosis
HIV/AIDS
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The overall objective of this study is to determine if a multi-component implementation intervention (SPIRIT) and additional leadership and management training that targets District Health Officers (D...
Detailed Description
The failure to use isoniazid (INH) preventative therapy (IPT) in HIV-infected individuals in Sub-Saharan Africa represents one of the single biggest implementation gaps between evidence and practice i...
Eligibility Criteria
Inclusion
- AIM 1 - Spirit Intervention:
- District Health Officer or TB District Supervisor (or other DHO-appointed TB focal person) in Uganda.
- By definition, the DHO or TB District Supervisor are all ≥18 years of age.
Exclusion
- Planned departure from position as DHO or TB District Supervisor prior to randomization.
- DHOs from Kampala and Wakiso districts, Uganda.
Key Trial Info
Start Date :
November 15 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 30 2023
Estimated Enrollment :
163 Patients enrolled
Trial Details
Trial ID
NCT03315962
Start Date
November 15 2017
End Date
November 30 2023
Last Update
June 18 2025
Active Locations (1)
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1
Infectious Diseases Research Collaboration
Kampala, Uganda