Status:
TERMINATED
US Guided GNB vs Saline Injection for TKA
Lead Sponsor:
Northwestern University
Conditions:
Postoperative Pain
Total Knee Arthroplasty
Eligibility:
All Genders
40-85 years
Phase:
PHASE4
Brief Summary
Do ultrasound-guided genicular nerve blocks with 0.5% bupivacaine provide improved knee analgesia for patients recovering from total knee replacement surgery compared to saline injection? Hypotheses:...
Detailed Description
The study medication and protocol will consist of Group 1 (Active) - ultrasound-guided adductor canal blockade with 10 ml of 0.25% bupivacaine and ultrasound-guided genicular nerve blocks with 6 ml of...
Eligibility Criteria
Inclusion
- Participants 40 to 85 years old who are presenting for minimally invasive total knee arthroplasty under spinal anesthesia and are candidates for peripheral nerve blocks.
- Minimally invasive is defined as custom modified instrumentation, a quadriceps sparing arthrotomy that does not extend beyond 1cm proximal to the patella and surgical techniques that focus on soft tissue protection.
Exclusion
- Patient refusal
- American Society of Anesthesiologists physical status classification of 4 or higher
- Pre-existing neuropathy in the femoral or sciatic distribution
- Coagulopathy
- Infection at the site
- Chronic opioid use (greater than 3 months)
- Pregnancy
- Medical conditions limiting physical therapy participation
- Any other contra-indication to regional anesthesia
Key Trial Info
Start Date :
October 5 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 21 2021
Estimated Enrollment :
2 Patients enrolled
Trial Details
Trial ID
NCT03316118
Start Date
October 5 2017
End Date
June 21 2021
Last Update
September 28 2022
Active Locations (1)
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1
Northwestern University
Chicago, Illinois, United States, 60611