Status:
UNKNOWN
Comparison of CLSB With Sedation Versus General Endotracheal Anesthesia on Postoperative Outcomes in Elderly Patients Undergoing Hip Fracture Surgery
Lead Sponsor:
Shanghai 6th People's Hospital
Conditions:
Anesthesia Morbidity
Anesthesia; Adverse Effect
Eligibility:
All Genders
77+ years
Phase:
NA
Brief Summary
Hip fracture is a global public health problem. The postoperative mortality and disability rate of hip fracture is high, and early surgery is still the most effective treatment method, but these patie...
Eligibility Criteria
Inclusion
- Age ≥77 years old;
- First unilateral surgery for hip fracture including femoral neck, intertrochanteric or subtrochanteric fracture;
- Patient with planned hip fracture surgery within 24-72 h;
- Patient without peripheral nerve block within 24 h prior to surgery;
- The ability to receive written informed consent from the patient or patient's legal representative.
Exclusion
- Refuse to participate;
- Unable to perform nerve block;
- Multiple trauma, multiple fractures or other fractures outside the inclusion criteria, such as pathological fractures, pelvic fractures, femur fractures;
- Prosthetic fracture;
- Scheduled for bilateral hip fracture surgery;
- Usage of bone-cement fixation in the surgery;
- With recent cerebral stroke (\<3 months);
- Combined with active heart disease (unstable angina, acute myocardial infarction, recent myocardial infarction; decompensated heart failure; symptomatic arrhythmia; severe mitral or aortic stenotic heart disease);
- Patient with known severe lung and/or airway disease, acute respiratory failure, acute pulmonary infection, and acute attack of bronchial asthma;
- Current enrolment in another clinical trial;
- Contraindication for general endotracheal anesthesia(drug allergies to general anesthesia, difficult airway);
- Contraindication for lumbar and sacral plexus block(infection at the site of needle insertion, coagulopathy, allergy to local anesthetics).
Key Trial Info
Start Date :
December 4 2018
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2023
Estimated Enrollment :
1086 Patients enrolled
Trial Details
Trial ID
NCT03318133
Start Date
December 4 2018
End Date
December 31 2023
Last Update
August 26 2022
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Shanghai Sixth People's Hospital
Shanghai, Shanghai Municipality, China, 021