Status:

COMPLETED

Effect of a Modified Oxygen Mask Associated to Nasal Prongs During a High Flow Oxygenation Method

Lead Sponsor:

Laboratory of Movement, Condorcet, Tournai, Belgium

Conditions:

Oxygen Inhalation Therapy

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The aim of this study is to determine the effect (on PaO2) of a modified mask associated to nasal cannula used for high flow oxygenation.

Detailed Description

Study Design This is a single-center, randomized, blind investigator, 2-way crossover study design. Enrolled participants had severe hypoxia being treated at Intensive Care Unit associated with a hosp...

Eligibility Criteria

Inclusion

  • Inclusion Criteria:
  • Regardless of gender, at least 18 years of age and diagnosed with severe Hypoxia (PaO2/FiO2 \< 300 mm Hg), dyspnea with severe rest at stake accessory muscles of respiration, respiratory rate (RR) ≥ 25 CPM, PaCO2 ≤ 45 mmHg, patient with an arterial catheter and without hemodynamic instability, Glasgow Coma Scale ≥ 12/15, written consent. Participants were also required to have a sufficient level of education to understand study procedures and be able to communicate with site personnel.
  • Exclusion Criteria Patients were excluded if they Hypercapnia (\> 45 mm Hg with respiratory acidosis), cardiogenic pulmonary edema, COPD, pulmonary fibrosis, hypoventilation obesity syndrom, arterial pressure \< 60 mm Hg or treatment by epinephrine \> to 0,1 gamma/kg/minute, deterioration of awareness (Glasgow scale \< or = 12), acute confusional state.
  • Participants were randomized in a 1:1 ratio to receive either (CHFONP) classical High Flow Oxygenation with nasal prongs (20 minutes) or CHFNOP with an adjunctive of a DTM.
  • \-

Exclusion

    Key Trial Info

    Start Date :

    February 1 2017

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    September 2 2017

    Estimated Enrollment :

    15 Patients enrolled

    Trial Details

    Trial ID

    NCT03319602

    Start Date

    February 1 2017

    End Date

    September 2 2017

    Last Update

    October 26 2017

    Active Locations (1)

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    epicura Hornu

    Hornu, Hainaut, Belgium, 7301