Status:

UNKNOWN

Benefits of Hemodialysis With Citrate (ABC-treat) Study

Lead Sponsor:

Fundación Senefro

Collaborating Sponsors:

Baxter Healthcare Corporation

Conditions:

Hemodialysis-Induced Symptom

Eligibility:

All Genders

18-99 years

Phase:

NA

Brief Summary

Prospective randomized cross-over multicenter study to demonstrate the benefits of hemodialysis without acetate dialysate, with citrate. 32 weeks duration, in two phases. In the first, half of the pa...

Detailed Description

Primary objective: to analyze the effect of citrate dialysate on acid base balance decreasing chronic metabolic acidosis and avoiding / reducing post-dialytic alkalosis. Secondary objectives: * Eval...

Eligibility Criteria

Inclusion

  • Outpatient conventional hemodialysis three times per week for at least three months.
  • Arteriovenous fistula as vascular access
  • Patients who have given their informed consent in writing.

Exclusion

  • Catheter as vascular access
  • Allergy or intolerance to citrate
  • Patients with sufficient cognitive impairment that would prevent the compression of information and informed consent.
  • Inflammatory intercurrent diseases (chronic infections, autoimmune diseases or tumors) that can mask the results of the study.

Key Trial Info

Start Date :

May 1 2016

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2017

Estimated Enrollment :

90 Patients enrolled

Trial Details

Trial ID

NCT03319680

Start Date

May 1 2016

End Date

December 1 2017

Last Update

October 24 2017

Active Locations (12)

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Page 1 of 3 (12 locations)

1

Hospital General de Castellón

Castellon, Castellón, Spain, 12004

2

Hospital del Henares

Coslada, Madrid, Spain, 28822

3

Hospital Universitario Infanta Sofía

San Sebastián de los Reyes, Madrid, Spain, 28702

4

Hospital Universitario Santa Lucía

Cartagena, Murcia, Spain, 30202