Status:

COMPLETED

EMD for Treatment of Proximal Class-II Furcation Involvements

Lead Sponsor:

Universidade Estadual Paulista Júlio de Mesquita Filho

Conditions:

Generalized Aggressive Periodontitis

Eligibility:

All Genders

18-35 years

Phase:

NA

Brief Summary

The aim of the present study is to evaluate the clinical response of proximal furcations treated with enamel matrix derivative proteins (EMD).

Detailed Description

Proximal class-II furcation represents a challeng to periodontal therapy. Studies show that the ultrasonic non-surgical therapy doesn't work in these defects and the guided tissue regeneration therapy...

Eligibility Criteria

Inclusion

  • Diagnosis of generalized aggressive periodontitis (Armitage, 1999; American Academy of Periodontology, 2015);
  • Have undergone a first approach for periodontal treatment (full-mouth ultrasonic debridement);
  • Presence of one proximal class-II furcation presenting probing depth \> 4 mm and bleeding on probing ;
  • Good general health;
  • Agree to participate in the study and sign the informed consent form (TCLE) after explaining the risks and benefits;

Exclusion

  • Systemic problems (cardiovascular alterations, blood dyscrasias, immunodeficiency - ASA III / IV / V) that contraindicate the periodontal procedure;
  • Have used antibiotics and anti-inflammatories in the last six months;
  • Smoke ≥ 10 cigarettes/day;
  • Pregnant or lactating;
  • Chronic use of medications that may alter the response of periodontal tissues;
  • Indication of antibiotic prophylaxis for dental procedures;

Key Trial Info

Start Date :

October 20 2017

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 20 2019

Estimated Enrollment :

34 Patients enrolled

Trial Details

Trial ID

NCT03320135

Start Date

October 20 2017

End Date

May 20 2019

Last Update

June 5 2019

Active Locations (1)

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1

Naira Andere

São José dos Campos, São Paulo, Brazil, 12245010