Status:
COMPLETED
Long-term Efficacy of Ablative Fractional Laser-assisted Photodynamic Therapy for Treatment of Lower Extremity Bowen's Disease
Lead Sponsor:
Dong-A University
Conditions:
Bowen's Disease
Eligibility:
All Genders
42-89 years
Phase:
PHASE1
Brief Summary
Er:YAG ablative fractional laser-assisted methyl aminolevulinate photodynamic therapy (AFL-PDT) has shown significantly higher efficacy and a lower recurrence rate at 12 months than methyl aminolevuli...
Detailed Description
To compare the long-term efficacy and recurrence rates of AFL-PDT and standard MAL-PDT for the treatment of lower extremity BD.
Eligibility Criteria
Inclusion
- •Patients aged 18 years or more who diagnosed as bowen's disease
Exclusion
- pregnancy or lactation
- active systemic infectious disease
- other inflammatory, infectious, or neoplastic skin diseases in the treated area
- allergy to MAL,other topical photosensitizers, or excipients of the cream
- history of photosensitivity
- use of immunosuppressive or photosensitizing drugs
- participation in any other investigational study in the preceding 30 days
- history or indicators of poor compliance
- Histological findings of acantholysis, desmoplasia, perineural or lymphovascular invasion, and echographic features of regional lymph node metastasis were the disease-specific exclusion criteria
Key Trial Info
Start Date :
October 30 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 19 2017
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT03320447
Start Date
October 30 2011
End Date
October 19 2017
Last Update
October 25 2017
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