Status:

COMPLETED

Impact of Neurological Diseases on the Prognosis of Bullous Pemphigoid: A Retrospective Study of 178 Patients

Lead Sponsor:

CHU de Reims

Conditions:

Bullous Pemphigoid

Eligibility:

All Genders

18+ years

Brief Summary

Bullous pemphigoid affects mainly elderly patients. It is often associated with neurologic disorders, which represent a major risk factor of the disease

Detailed Description

The aim was to determine whether neurologic disorders, especially dementia, influences outcome and mortality of patients with bullous pemphigoid.

Eligibility Criteria

Inclusion

  • Inclusion Criteria:
  • patients presenting bullous pemphigoid using the following criteria: clinical features typical of BP with presence of at least three out of four well-established criteria of Vaillant et al., subepidermal blister on skin biopsy and deposits of IgG and/or C3 in a linear pattern along the epidermal basement membrane zone by direct IF
  • patients consulting at dermatology department of Reims Teaching Hospital (France) between 1997 and 2011

Exclusion

    Key Trial Info

    Start Date :

    October 1 2013

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ACTUAL

    End Date :

    March 1 2015

    Estimated Enrollment :

    178 Patients enrolled

    Trial Details

    Trial ID

    NCT03320798

    Start Date

    October 1 2013

    End Date

    March 1 2015

    Last Update

    October 25 2017

    Active Locations (1)

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    1

    Damien JOLLY

    Reims, France