Status:
RECRUITING
Cortical Spreading Depolarization After Severe Traumatic Brain Injury
Lead Sponsor:
Hennepin County Medical Center, Minneapolis
Conditions:
Traumatic Brain Injury
Eligibility:
All Genders
18+ years
Brief Summary
Preliminary evaluation of electrodes placed on the brain for recording brain activity and novel algorithms to determine cortical spreading depolarization foci of origination following severe traumatic...
Detailed Description
The goal of this study is to improve our understanding of cortical spreading depolarizations (CSDs) as a mechanism of secondary injury in severe traumatic brain injury (TBI). The primary obstacles to ...
Eligibility Criteria
Inclusion
- Patient recommended to undergo craniectomy or craniotomy for the treatment of acute TBI
Exclusion
- Wound determined to be contaminated
- Decompression is performed only in the posterior fossa
- Known systemic infection
- Pregnancy
Key Trial Info
Start Date :
August 14 2019
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
November 1 2025
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT03321370
Start Date
August 14 2019
End Date
November 1 2025
Last Update
September 12 2025
Active Locations (1)
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1
Hennepn Healthcare
Minneapolis, Minnesota, United States, 55404