Status:
UNKNOWN
Treatment of Chronic Renal Failure With Adipose Tissue-derived Mesenchymal Stem Cells
Lead Sponsor:
The Affiliated Hospital of Xuzhou Medical University
Conditions:
Mesenchymal Stem Cells
Chronic Kidney Diseases
Eligibility:
All Genders
18-75 years
Phase:
NA
Brief Summary
To investigate the biological characteristics of adipose tissue-derived mesenchymal stem cells(AMSCs) and its treatment effects on chronic renal failure.
Detailed Description
This study aims to investigate the biological characteristics of adipose tissue-derived mesenchymal stem cells(AMSCs) and its effect on oxidative stress, inflammation and mitochondrial damage.We inten...
Eligibility Criteria
Inclusion
- Enroll the chronic renal failure patients without dialysis in the department of nephrology of Affiliated Hospital of Xuzhou Medical University from January 2017 to December 2018.
- The patients enrolled were not treated with drugs that affect the renal blood flow and oxygen consumption, such as ACEI, ARB, calcium channel blockers, diuretics, vasodilators and other related factors within 2 weeks.
Exclusion
- Exclude those patients with diabetes, cardiovascular disease, severe infection, shock, dehydration, abnormal liver function, received glucocorticoid therapy, surgery and emergency dialysis.
- Eliminate those patients with respiratory disease(such as chronic obstructive pulmonary disease, bronchiectasis, asthma), cardiovascular diseases(such as acute and chronic cardiac insufficiency), blood system diseases (such as aplastic anemia, nutritional anemia and polycythemia vera).
Key Trial Info
Start Date :
January 1 2017
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2018
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT03321942
Start Date
January 1 2017
End Date
December 31 2018
Last Update
October 26 2017
Active Locations (1)
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1
The Affiliated Hospital of Xuzhou Medical University
Xuzhou, Jiangsu, China, 221000