Status:
COMPLETED
Effect of Atropine or Glycopyrrolate on the Prevention of Bradycardia During Sedation Using Dexmedetomidine in Geriatric Patients Undergoing Total Knee Replacement Under Spinal Anesthesia
Lead Sponsor:
Yonsei University
Conditions:
Spinal Anesthesia
Eligibility:
All Genders
65+ years
Phase:
NA
Brief Summary
Patients undergoing total knee arthroplasty with spinal anesthesia are often sedated to reduce patient discomfort due to large noises during surgery and also to reduce anxiety. Most commonly used seda...
Eligibility Criteria
Inclusion
- Patients 65 years or older undergoing total knee replacement surgery under spinal anesthesia.
- ASA class 1-3
Exclusion
- Patients with coagulation abnormalities
- End organ diseases of liver, lung or kidney
- Severe aortic stenosis
- High degree AV block
- Heart failure
- Patients on MAO inhibitors
- History of seizures or epilepsy
- Glaucoma
Key Trial Info
Start Date :
October 16 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 15 2018
Estimated Enrollment :
54 Patients enrolled
Trial Details
Trial ID
NCT03322098
Start Date
October 16 2017
End Date
May 15 2018
Last Update
September 24 2018
Active Locations (1)
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1
Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of Medicine
Seoul, South Korea, 03722