Status:

ENROLLING_BY_INVITATION

Establishment of Genetic Basis for Neurological Disease by Genetic Screening

Lead Sponsor:

Chinese University of Hong Kong

Conditions:

Neuro-Degenerative Disease

Eligibility:

All Genders

18-80 years

Brief Summary

Hereditary neurological disorders are relatively common in paediatric neurological practice, but it has considerable overlap with adult neurological disorders. It is a group of of genetic diseases, mo...

Detailed Description

The human iPS is generated by direct reprogramming of human somatic cells. These hiPS cells can give rise to most tissue types in the human embryo and possess many of the properties of human embryonic...

Eligibility Criteria

Inclusion

  • Individuals at age 18 years or older who have presumed hereditary neurological disease.
  • Individuals or his/her guardian who can provide the informed consent.

Exclusion

  • Individuals who are allergic to local anesthetics.
  • Individuals who have serious medical conditions that restrict their ability to tolerate skin biopsy.
  • Individuals who have history of bleeding diathesis or use of anticoagulant medications. Patients taking nonsteroidal anti-inflammatory agents will be asked to discontinue these medications 3 days prior to skin biopsy.

Key Trial Info

Start Date :

November 16 2012

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 31 2025

Estimated Enrollment :

200 Patients enrolled

Trial Details

Trial ID

NCT03322306

Start Date

November 16 2012

End Date

December 31 2025

Last Update

August 27 2024

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Prince of Wales Hospital

Hong Kong, Shatin, Hong Kong, 000