Status:
UNKNOWN
Receiving Modified Chemotherapy Followed With Radical Resection After Neoadjuvant Chemotherapy
Lead Sponsor:
Peking Union Medical College Hospital
Conditions:
Locally Advanced Gastric Cancer
Eligibility:
All Genders
18-75 years
Phase:
PHASE2
Brief Summary
For patients undergoing postoperative therapy for locally advanced gastric cancer after neoadjuvant chemotherapy, we assessed the utility of graded histologic regression of \<50% as the criterion of t...
Detailed Description
For patients undergoing postoperative therapy for locally advanced gastric cancer after neoadjuvant chemotherapy, we assessed the utility of graded histologic regression of \<50% as the criterion of t...
Eligibility Criteria
Inclusion
- TNM stage of T2-T4 or positive regional lymph nodes, according to the American Joint Committee on Cancer (AJCC) 7.0 staging system, verified by enhanced abdominal computed tomography (CT) and/or endoscopic ultrasound (EUS), positron emission tomography (PET)/CT scan), with no evidence of distant metastases;
- ECOG performance status score ≤2 without serious heart, lung, liver, kidney, or hematological dysfunctions;
- age ≥18 years old;
- no previous chemotherapy, radiotherapy, or surgical treatment for gastric cancer;
- gastrectomy was performed after preoperative chemotherapy if imaging studies did not confirm disease progression (according to the Response Evaluation Criteria in Solid Tumors (RECIST)) ;
- signed the informed consent form.
Exclusion
- All do not reach the inclusion criteria
Key Trial Info
Start Date :
August 23 2017
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
August 1 2023
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT03322969
Start Date
August 23 2017
End Date
August 1 2023
Last Update
February 26 2021
Active Locations (1)
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1
Department of Medical Oncology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences
Beijing, Beijing Municipality, China, 100032