Status:

UNKNOWN

Efficacy and Tolerability of Hemopatch After Hepatic Resection

Lead Sponsor:

Fondazione Policlinico Universitario Agostino Gemelli IRCCS

Collaborating Sponsors:

Baxter Healthcare Corporation

Conditions:

Hepatectomy

Cancer, Metastatic

Eligibility:

All Genders

18-75 years

Phase:

NA

Brief Summary

* Previous in vitro and in vivo studies detected the Hemopatch Sealing Hemostat® to be a new versatile, self-adhering hemostatic sealing pad consisting of a polyethylene glycol-coated collagen. * Init...

Detailed Description

Advances in surgical techniques have reduced the occurrence of postoperative complications following liver resection and resulted in low surgical mortality and morbidity rates in high-volume centers. ...

Eligibility Criteria

Inclusion

  • Hepatocellular carcinoma
  • Hilar cholangiocarcinoma
  • Adrenal cancer metastasis
  • Breast cancer metastasis
  • Colorectal cancer metastasis
  • Ovarian cancer metastasis
  • Biliary carcinoma
  • Hemangioma
  • Hepatic adenoma
  • Focal nodular hyperplasia
  • Unilocular hydatid cyst
  • Multilocular hydatid cyst

Exclusion

  • Trauma surgery
  • Active sepsis around the liver
  • Documented history of cirrhosis
  • Pregnant or nursing women
  • Severe coagulopathy (defined as an International normalized ratio \>2.0)
  • Severe Liver disfunction, as per clinical assessment
  • Previous liver transplantation
  • Laparoscopic procedure
  • Any other intraoperative finding, which defines the no eligibility of the patient for liver resection
  • Known hypersensitivity to bovine proteins or brilliant blue
  • Mental condition rendering the patient unable to understand the nature, scope and possible consequences of the study

Key Trial Info

Start Date :

March 17 2017

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

March 17 2019

Estimated Enrollment :

98 Patients enrolled

Trial Details

Trial ID

NCT03323359

Start Date

March 17 2017

End Date

March 17 2019

Last Update

November 8 2017

Active Locations (1)

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Policlinico Universitario Agostino Gemelli

Rome, Italy, 00168