Status:
UNKNOWN
Effects of High-intensity Interval Training (HIIT) in Recent Onset Polymyositis and Dermatomyositis
Lead Sponsor:
Karolinska University Hospital
Collaborating Sponsors:
Karolinska Institutet
Conditions:
Polymyositis
Dermatomyositis
Eligibility:
All Genders
18-70 years
Phase:
NA
Brief Summary
Polymyositis and dermatomyositis are rare inflammatory systemic conditions. Reduced muscle function is a cardinal symptom and lung involvement is very common. Knowledge of heart involvement in these p...
Detailed Description
Patients randomized to the HIIT protocol will train three days a week for 12 weeks. Before exercise start participants will rate self-reported pain and fatigue on a visual analogue scale and describe ...
Eligibility Criteria
Inclusion
- Patients with polymyositis and dermatomyositis:
- Probable or definite diagnosis polymyositis or dermatomyositis according to Bohand and Peter criteria, diagnosis duration between 4 weeks and 6 months, completed screening for possible concurrent cancer diagnosis and screening for lung involvement, able to performe the HIIT.
Exclusion
- Diagnosis of inclusion body myositis, active cancer, being treated for cancer, heart- or lung involvement contraindicating HIIT, no clinical improvement with medical treatment, severe osteoporosis.
- Healthy controls:
- Inclusion Criteria: match a patient for age and gender, exercising not more than twice a week, no neuro- or musculoskeletal disorders.
Key Trial Info
Start Date :
October 1 2017
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2021
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT03324152
Start Date
October 1 2017
End Date
December 31 2021
Last Update
April 23 2018
Active Locations (1)
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1
Karolinska University Hospital
Stockholm, N/A = Not Applicable, Sweden, Se-171 76