Status:

UNKNOWN

Effect of Dietary Modifacation on Microbiota in Overweight and Obese Polycystic Ovary Syndrome Patients

Lead Sponsor:

Poznan University of Medical Sciences

Collaborating Sponsors:

University of California, San Diego

Sanprobi

Conditions:

PCOS

Eligibility:

FEMALE

18-40 years

Phase:

PHASE4

Brief Summary

Polycystic ovary syndrome (PCOS) is the most common endocrinopathy affecting women of reproductive age. The pathogenesis of PCOS is not fully understood. The intestinal microbiota are believed to be a...

Detailed Description

Polycystic ovary syndrome (PCOS) is the most common endocrinopathy affecting women of reproductive age. The pathogenesis of PCOS is not fully understood. The intestinal microbiota are believed to be a...

Eligibility Criteria

Inclusion

  • Written consent for participation in the clinical trial
  • Age 18 to 45 years Irregular menstruation (\> 35 days) or secondary amenorrhea\> 3 months
  • 4\. Hyperandrogenism (hirsutism and / or acne) and / or hyperandrogenemia (total serum testosterone\> 0.5 ng / mL) 5. BMI \> 25

Exclusion

  • Ovarian cancer, adrenal gland tumor, endometrial cancer, cervical cancer, breast cancer
  • Congenital adrenal hyperplasia (17-OH-progesterone\> 2.5 ng / mL)
  • Clinically diagnosed Cushing's disease, acromegaly, gigantism
  • Type I or II diabetes
  • Unexplained bleeding from the genital tract
  • Hormone treatment within the last 2 months

Key Trial Info

Start Date :

May 20 2017

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

October 20 2018

Estimated Enrollment :

80 Patients enrolled

Trial Details

Trial ID

NCT03325023

Start Date

May 20 2017

End Date

October 20 2018

Last Update

October 30 2017

Active Locations (1)

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1

Division of Infertility and Reproductive Endocrinology, Department of Gynecology and Obsterics

Poznan, Poland, 61701