Status:
TERMINATED
Assessing the Effects of Increased Mitochondrial Function Exercise Training on Muscle Performance
Lead Sponsor:
University of Exeter
Collaborating Sponsors:
Royal Devon and Exeter NHS Foundation Trust
Conditions:
Impaired Mitochondrial Function, Muscle Performance
Eligibility:
MALE
65-75 years
Phase:
NA
Brief Summary
As people grow older skeletal muscle gradually becomes smaller and weaker, causing reduced mobility and quality of life. To understand and reverse this negative process investigators need to find new ...
Eligibility Criteria
Inclusion
- Male
- Age between 65-75 years
- Body mass index between 19-29
- No active cardiovascular or metabolic disease
- No active respiratory disease
- No current musculoskeletal injuries
- A sedentary lifestyle (i.e. does not engage in strenuous, planned physical activity)
- The ability to give informed consent
Exclusion
- Currently taking a statin drug or NSAIDs
- Have a current peptic ulcer
- Have any renal impairment
- Have a known hypersensitivity to Acipimox
- Suffer from vertigo
- Smoker
Key Trial Info
Start Date :
March 7 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 16 2019
Estimated Enrollment :
2 Patients enrolled
Trial Details
Trial ID
NCT03325491
Start Date
March 7 2018
End Date
September 16 2019
Last Update
September 27 2019
Active Locations (1)
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1
NIHR Exeter Clinical Research Facility
Exeter, Devon, United Kingdom, EX2 5DW