Status:

COMPLETED

Clinical Trial to Evaluate the Symptoms in Symptomatic Contact Lens Wearers Following Application of Intranasal Tear Neurostimulator Versus Control

Lead Sponsor:

Allergan

Conditions:

Dry Eye Syndromes

Eligibility:

All Genders

22+ years

Phase:

NA

Brief Summary

This study will evaluate the increase in comfort and comfortable contact lens (CL) wear time associated with application of TrueTear (active intranasal neurostimulation) compared with application of T...

Eligibility Criteria

Inclusion

  • A person is eligible for inclusion if he/she
  • In at least one eye, has a cotton swab nasal stimulation Schirmer test score at least 4 mm greater than 3 minute Schirmer with anesthesia basal score in the same eye at the Screening Visit
  • Is an adapted soft contact lens wearer and currently wears lenses an average of at least 2 days per week, with an average minimum wearing time of 3 hours each day over the past month and is able and willing to wear lenses for at least 6 hours on four study day visits
  • Has at least 20/40 visual acuity in both eyes with CL correction
  • Is symptomatic according to Young's categorization

Exclusion

  • Refractive error surgery
  • Chronic or recurrent epistaxis, coagulation disorders or other conditions that may increase the risk of bleeding
  • History of nasal or sinus surgery
  • Vascularized polyp, deviated septum or severe nasal airway obstruction at the Screening visit
  • Cardiac demand pacemaker, implanted defibrillator, or other active implanted metallic or active implanted electronic device in the head

Key Trial Info

Start Date :

November 22 2017

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 29 2018

Estimated Enrollment :

84 Patients enrolled

Trial Details

Trial ID

NCT03325673

Start Date

November 22 2017

End Date

November 29 2018

Last Update

December 18 2019

Active Locations (1)

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1

Centre for Contact Lens Research School of Optometry & Vision Science, University of Waterloo

Waterloo, Ontario, Canada, N2L 3G1