Status:
COMPLETED
Efficacy in Ablative Fractional Laser Assisted Photodynamic Therapy According to Ablative Depth for Actinic Keratosis
Lead Sponsor:
Dong-A University
Conditions:
Actinic Dermatosis
Eligibility:
All Genders
60-85 years
Phase:
PHASE1
Brief Summary
Er:YAG ablative fractional laser-assisted photodynamic therapy (AFL-PDT) has shown significant benefit for the treatment of actinic keratosis(AK). Er:YAG ablative fractional laser ablates the epidermi...
Detailed Description
The investigators aimed to investigate whether the use of increased laser ablative depth affects the efficacy, side effects, cosmetic outcomes, and PPIX accumulation of AFL-PDT for facial AK in a rand...
Eligibility Criteria
Inclusion
- Korean patients aged ≥ 18 years who had biopsy-confirmed Actinic keratosis lesions
Exclusion
- photosensitivity disorder patients
- lactating or pregnant women
- patients with porphyria or a known allergy to any of the constituents of the MAL cream and lidocaine
- patients with systemic disease, history of malignant melanoma, tendency of melasma development or keloid formation, any AK treatment of the area in the previous 4 weeks, or any conditions associated with a risk of poor protocol compliance; and patients on immunosuppressive treatment
Key Trial Info
Start Date :
September 1 2015
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 20 2017
Estimated Enrollment :
45 Patients enrolled
Trial Details
Trial ID
NCT03325803
Start Date
September 1 2015
End Date
September 20 2017
Last Update
October 31 2017
Active Locations (1)
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1
Dong-A University
Busan, Seo-gu, Korea, Republic Of, 602-715, South Korea