Status:
COMPLETED
Prehospital High-Flow Nasal Oxygen Therapy
Lead Sponsor:
Centre Hospitalier Régional d'Orléans
Conditions:
Acute Respiratory Failure With Hypoxia
Oxygen Inhalation Therapy
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The purpose of the present project is to compare High-Flow Nasal Oxygen therapy with Standard Oxygen therapy, initiated in the prehospital setting in patients with acute hypoxemia respiratory failure,...
Detailed Description
Patients with respiratory distress and an SpO2 below 90% in the prehospital setting will be randomized to receive either high-flow nasal oxygen therapy through a dedicated device or standard oxygen th...
Eligibility Criteria
Inclusion
- Age ≥ 18 years
- First SpO2 on scene \<90%
- At least one other sign of respiratory distress defined by (a) respiratory distress with a respiratory rate ≥ 25/min; (b) laboured breathing
- No advance directives or known decisions of Do Not intubate or Do Not Ventilate order.
Exclusion
- Known COPD or other hypercapnic chronic respiratory failure
- age \<18 years
- Pregnancy or breastfeeding
- Anatomical factors precluding the use of a nasal cannula
- Emergency intubation required
- Patients with tracheostomy
- Patient transported to a hospital not involved in the study
Key Trial Info
Start Date :
December 21 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 10 2022
Estimated Enrollment :
58 Patients enrolled
Trial Details
Trial ID
NCT03326830
Start Date
December 21 2017
End Date
August 10 2022
Last Update
February 17 2023
Active Locations (2)
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1
CHR d'ORLEANS
Orléans, France
2
Brigade des Sapeurs Pompiers de Paris
Paris, France