Status:

COMPLETED

ET-01 in Subjects With Lateral Canthal Lines

Lead Sponsor:

Eirion Therapeutics Inc.

Conditions:

Lateral Canthal Lines

Crow's Feet

Eligibility:

All Genders

25-65 years

Phase:

PHASE2

Brief Summary

This study tests an investigational drug formulation called ET-01, botulinum toxin, Type A, topical, in lateral canthal lines (LCL).

Detailed Description

This product is being tested for its ability to reduce lateral canthal lines, also known as Crow's Feet.

Eligibility Criteria

Inclusion

  • 25 - 65 years of age
  • minimal to moderate Crow's Feet wrinkles at rest
  • moderate to severe Crow's Feet wrinkles on contraction
  • willingness to refrain from any product affecting skin remodeling
  • female subjects must be not pregnant and non-lactating-

Exclusion

  • history of adverse reactions to any prior botulinum toxin treatments
  • history of vaccination or non-response to any prior botulinum toxin treatments
  • botulinum toxin treatment in the prior 6 months
  • present or history of neuromuscular disease, eyelid ptosis, muscle weakness, paralysis, or "dry eye"
  • history of peri-ocular surgery, brow lift or related procedures
  • procedures affecting the lateral canthal region in the prior 12 months
  • application of topical prescription medication to the treatment area
  • female subjects who are pregnant or are nursing a child

Key Trial Info

Start Date :

October 25 2017

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 14 2018

Estimated Enrollment :

48 Patients enrolled

Trial Details

Trial ID

NCT03326856

Start Date

October 25 2017

End Date

November 14 2018

Last Update

April 21 2022

Active Locations (1)

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Cary Skin Care

Cary, North Carolina, United States, 27519