Status:

WITHDRAWN

Impact of Local Steroid Application in Extreme Lateral Lumbar Interbody Fusion

Lead Sponsor:

Rush University Medical Center

Conditions:

Stenosis

Herniated Nucleus Pulposus

Eligibility:

All Genders

Phase:

PHASE3

Brief Summary

Neural injury is a well-known complication following extreme lateral lumbar interbody fusion (XLIF). It has been found that up to 9.4% of patients will have either temporary or persistent neurologic d...

Detailed Description

The purpose of this study is to determine if the incidence and duration of postoperative pain is reduced in the subjects receiving a local injection of methylprednisolone when compared to placebo foll...

Eligibility Criteria

Inclusion

  • Patients undergoing a 1- to 2-level XLIF
  • Diagnosis: myelopathy, radiculopathy, myeloradiculopathy, stenosis, herniated nucleus pulposus, degenerative disc disease, spondylosis, osteophytic complexes, and foraminal stenosis
  • Patients able to provide informed consent

Exclusion

  • Allergies or other contraindications to medicines in the protocol including:
  • Existing history of gastrointestinal bleeding
  • Lumbar spine trauma
  • Unable to speak, read, or understand English

Key Trial Info

Start Date :

May 22 2018

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 24 2020

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT03327272

Start Date

May 22 2018

End Date

July 24 2020

Last Update

November 20 2020

Active Locations (1)

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Rush University Medical Center

Chicago, Illinois, United States, 60612