Status:
WITHDRAWN
Early Flu Shots in SOT
Lead Sponsor:
University Health Network, Toronto
Conditions:
Influenza
Solid Organ Transplant
Eligibility:
All Genders
18+ years
Brief Summary
Although time from transplant has been a factor in vaccine response, there is limited data on immunizations that occur in the first post-transplant year, and there are no data that suggest influenza v...
Detailed Description
Influenza virus is an important cause of morbidity in the transplant population and can lead to viral and bacterial pneumonia. Influenza vaccine is effective in the prevention of influenza infection a...
Eligibility Criteria
Inclusion
- Kidney, liver or pancreas transplant recipients on at least one immunosuppressive medication
- Age ≥ 18
- Outpatient status
- Greater than 30 days post-transplant
Exclusion
- Has already received influenza vaccination for 2017-2018 season
- Egg allergy or allergy to previous influenza vaccine
- Febrile illness in the past one week
- Active Cytomegalovirus viremia
- Use of Rituximab in the past one year
- Ongoing or recent (in past 30 days) therapy for acute rejection
- Chronic kidney insufficiency (creatinine clearance ≤30mL/min or dialysis-dependent
- Previous life-threatening reaction to influenza vaccine (i.e., Guillain Barre Syndrome)
- Receipt of intravenous immunoglobulin (IVIG) in the past 30 days or planning to receive IVIG in the next four weeks
Key Trial Info
Start Date :
May 7 2019
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
May 7 2019
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT03327987
Start Date
May 7 2019
End Date
May 7 2019
Last Update
October 20 2020
Active Locations (1)
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1
University Health Network, Toronto General Hospital, Multi-Organ Transplant
Toronto, Ontario, Canada, M5G2N2