Status:
RECRUITING
Effects of Variation of Sodium Dialysate in ICU
Lead Sponsor:
University Hospital, Montpellier
Conditions:
Acute Kidney Injury
Renal Replacement Therapy
Eligibility:
All Genders
18-80 years
Phase:
PHASE2
Brief Summary
Intermittent hemodialysis/diafiltration is a current renal replacement therapy (RRT) institued for ICU patients with AKI. For a better clinical tolerance, iinternational guidelines advise to use cold ...
Detailed Description
Acute kidney injury (AKI) requiring renal replacement therapy (RRT) occurs in 5 to 6% of critically ill patients and is associated with high mortality and significant health resource utilization. Moda...
Eligibility Criteria
Inclusion
- Inclusion criteria:
- Age \> 18 years old
- Acute kidney injury requiring renal replacement therapy
- Dialysis type: on line sustained low efficiency dialy dialysis -filtration
- SOFA score \> 5
- Sodium serum level between 135 and 145mmol/l
- Exclusion criteria:
- Chronic kidney disease stade IV ou V
- Obstrutive acute kidney injury
- Renal tansplantation in the year before ICU admission
- Moribund with risk of death in the 48 hours
- Vulnerable persons or protected persons
- Pregnant or breastfeeding mother
Exclusion
Key Trial Info
Start Date :
April 19 2018
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 19 2026
Estimated Enrollment :
158 Patients enrolled
Trial Details
Trial ID
NCT03329313
Start Date
April 19 2018
End Date
December 19 2026
Last Update
September 30 2025
Active Locations (1)
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1
Uhmontpellier
Montpellier, Montpellier, France, 34295