Status:

UNKNOWN

Laparoscopic Right Hemicoloectomy for Right Colon Cancer With a Medial-to-lateral Approach Orientated by SMA or SMV

Lead Sponsor:

The First Affiliated Hospital with Nanjing Medical University

Conditions:

Right Colic Lymphadenopathy

Eligibility:

All Genders

18-85 years

Phase:

PHASE2

PHASE3

Brief Summary

A randomized controlled clinical trial to compare the outcomes of SMA- and SMV- orientated laparoscopic right hemicoloectomy for right colon cancer with a medial-to-lateral approach

Detailed Description

In 2008, Germany scholar W. Hohenberger proposed the idea of complete mesocolic excision (CME) and central vascular ligation (CVL) for the standardization of colonic cancer surgery. This concept has b...

Eligibility Criteria

Inclusion

  • Patients suitable for curative surgery between 18 - 85 years old;
  • American Society of Anesthesiologists(ASA) grade I-III;
  • Preoperative pathological diagnosis of adenocarcinoma;
  • Tumor located at the right colon;
  • Informed consent;
  • No history of familial adenomatous polyposis, ulcerative colitis or Crohn's disease.

Exclusion

  • Pregnant patient;
  • History of psychiatric disease;
  • Use of systemic steroids;
  • Simultaneous multiple primary colorectal cancer;
  • Preoperative enhanced CT scan of chest, abdominal and pelvic cavity shows:
  • Tumor involves the surrounding organs and combined organ resection needed to be done;
  • distant metastasis;
  • unable to perform R0 resection;
  • History of any other malignant tumor in recent 5 years;
  • Patients need emergency operation: mechanic ileus, perforation.
  • Not suitable for laparoscopic surgery (i.e., extensive adhesion caused by abdominal surgery, not suitable for artificial pneumoperitoneum, etc).
  • Conversion from laparoscopic surgery to laparotomy;

Key Trial Info

Start Date :

January 1 2018

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

January 1 2023

Estimated Enrollment :

200 Patients enrolled

Trial Details

Trial ID

NCT03329495

Start Date

January 1 2018

End Date

January 1 2023

Last Update

November 6 2017

Active Locations (1)

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1

Jiangsu province hospital

Nanjing, Jiangsu, China, 210029