Status:
UNKNOWN
Gluten Related Disorders in Barrett's Esophagus
Lead Sponsor:
McMaster University
Conditions:
Celiac Disease
Barrett Esophagus
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
In a small group of people gluten, a storage protein commonly in wheat and other grains, can cause gut inflammation and symptoms like diarrhea and abdominal pain. Gluten-related disorders include celi...
Detailed Description
Perhaps patient's with gluten related disorders develop Barrett's esophagus due to non-acid reflux precipitated by upper gastrointestinal motility changes that respond to a gluten free diet; whereas p...
Eligibility Criteria
Inclusion
- Aged 18 years and over
- Barrett's Esophagus diagnosis based on endoscopy and esophageal biopsies
- Patients able to comply to the study procedures, according to the investigator's own judgment
Exclusion
- Patients who have been on a gluten free diet within the last six months
- History of bariatric surgery, fundoplication, or gastrectomy (partial or complete)
- Connective tissue disease
- Concurrent organic GI pathology other than benign polyps, haemorrhoids, lipomas, H. pylori infection, diverticulosis, and melanosis coli
- Chronic treatment with high dose opioids
- Alcohol or drug abuse
- Pregnant or breastfeeding women. Women enrolling in the study will be advised to avoid pregnancy during the course of the study by using adequate birth control such as abstinence, oral contraceptive pill, barrier contraceptives (i.e condom). If a subject becomes pregnant she will be withdrawn from the study.
- Concurrent systemic disease and/or laboratory abnormalities considered by investigators to be a risk or that could interfere with data collection
Key Trial Info
Start Date :
April 1 2018
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 30 2018
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT03329534
Start Date
April 1 2018
End Date
December 30 2018
Last Update
March 21 2018
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