Status:

UNKNOWN

Effect of Haemodialysis on the Efficacy of Antiplatelet Agents

Lead Sponsor:

The First Affiliated Hospital with Nanjing Medical University

Conditions:

Renal Failure

Coronary Artery Disease

Eligibility:

All Genders

Brief Summary

The main purpose of our study is to investigate whether haemodialysis itself affects the efficacy of antiplatelet drugs and the effects of two different types of dialysis membranes (polysulfone membra...

Eligibility Criteria

Inclusion

  • diagnosis of coronary heart disease including stable angina, unstable angina, acute myocardial infarction
  • taking dual antiplatelet drugs (clopidogrel 75mg qd + aspirin 100mg qd or ticagrelor 90 mg,bid + aspirin 100 mg,qd) at least 5 days
  • haemodialysis patients
  • sign informed consent

Exclusion

  • platelet count\>450 × 10 9 /L or \<100 × 10 9 /L
  • using IIb / IIIa inhibitor drugs within 10days
  • taking nonsteroidal anti-inflammatory drugs other than aspirin
  • hemorrhagic disease
  • allergic to aspirin, ticagrelor or clopidogrel
  • other factors may affect the results of this study

Key Trial Info

Start Date :

November 10 2017

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

September 1 2019

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT03330223

Start Date

November 10 2017

End Date

September 1 2019

Last Update

January 8 2018

Active Locations (1)

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First Affiliated Hospital of Nanjing Medical University

Nanjing, Jiangsu, China, 210029