Status:
COMPLETED
Comparison of Two Strategies for Endotracheal Tube Cuff Underinflation Prevention During Invasive Mechanical Ventilation
Lead Sponsor:
Nantes University Hospital
Conditions:
Acute Brain Injury
Brain Injuries
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
During invasive mechanical ventilation, maintaining endotracheal tube cuff pressure (Pcuff) around 25 cmH2O is recommended for sealing the upper airways. The continuous control of Pcuff with a simple ...
Detailed Description
During invasive mechanical ventilation, maintaining a tracheal cuff pressure (Pcuff) around 25 cmH2O is recommended to prevent cuff over- (\> 30 cmH2O) and underinflation (\< 20 cmH2O), identified as ...
Eligibility Criteria
Inclusion
- with severe acute brain damage
- admitted in the ICU for less than 48 hours
- and expected to receive invasive mechanical ventilation (through orotracheal tube with a low pressure-high volume cuff) for at least 48 hours after inclusion.
Exclusion
- change in the upper airway management within the 48 hours following the inclusion (extubation or change in the tracheal tube or tracheostomy)
- pregnancy, moribund status.
Key Trial Info
Start Date :
March 1 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 31 2019
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT03330379
Start Date
March 1 2018
End Date
July 31 2019
Last Update
September 4 2019
Active Locations (1)
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1
Chu de Nantes
Nantes, France, 44093