Status:
COMPLETED
Molecular Mediators of Physical Exercise and Carnosine Induced Effects in Patients With Preclinical and Early Stage Neurodegenerative Disease
Lead Sponsor:
Slovak Academy of Sciences
Collaborating Sponsors:
Comenius University
University Hospital Bratislava
Conditions:
Subjective Cognitive Impairment
Mild Cognitive Impairment
Eligibility:
All Genders
55-80 years
Phase:
NA
Brief Summary
The purpose of this study is to investigate the beneficial effects of regular exercise and the impact of food supplement carnosine on cognitive, motoric and metabolic functions as well as on specific ...
Detailed Description
Standard Operating Procedures for patient recruitment, data collection, data management, data analysis routinely used in Biomedical Research Center, Slovak Academy of Sciences, University Hospital Bra...
Eligibility Criteria
Inclusion
- Signed informed consent
- Age 55 - 80 years
- Presence of Subjective Cognitive Impairment (SCI), Mild Cognitive Impairment (MCI) or early stage of Parkinson's Disease (Hoehn-Yahr 1st-2nd stage), assessed by experienced neurologist
Exclusion
- Serious systemic cardiovascular, hepatic, renal disease, cancer
- Lack of compliance
Key Trial Info
Start Date :
January 1 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 30 2023
Estimated Enrollment :
26 Patients enrolled
Trial Details
Trial ID
NCT03330470
Start Date
January 1 2017
End Date
September 30 2023
Last Update
May 28 2025
Active Locations (3)
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1
University Hospital Bratislava, Comenius University
Bratislava, Slovakia, 81369
2
Biomedical Research Center, Slovak Academy of Sciences
Bratislava, Slovakia, 84505
3
Laboratory of Cognitive Neurophysiology, Institute of Physical Education, Health & Leisure Studies, National Cheng Kung University
Tainan, Tainan, Taiwan, 701