Status:

TERMINATED

Effect of Short-term Theta Frequency Stimulation of the Vagus Nerve on Cognition in Patients With Refractory Epilepsy

Lead Sponsor:

University of California, Davis

Conditions:

Refractory Epilepsy

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The purpose of this investigation is data pilot study of the effect of theta frequency stimulation of the vagus nerve on cognitive performance in patients with refractory epilepsy. We will compare the...

Eligibility Criteria

Inclusion

  • Diagnosis of Refractory Epilepsy
  • Previously implanted vagal nerve stimulator
  • Willingness and ability to undergo temporary changes to their VNS device settings

Exclusion

  • \<18 years of age
  • Adults unable to consent
  • Pregnant women
  • Prisoners
  • \>20 on the Beck Depression Inventory (BDI)
  • \<24 on the Montreal Cognitive Assessment (MOCA)
  • Adults with diagnosis of developmental delay, intellectual disability, or traumatic brain injury (TBI).
  • Adults with reported history of learning disability.
  • Adults unable to use a computer with their dominant hand.
  • Status Epilepticus within the past 6 months

Key Trial Info

Start Date :

January 6 2017

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 31 2017

Estimated Enrollment :

2 Patients enrolled

Trial Details

Trial ID

NCT03331939

Start Date

January 6 2017

End Date

October 31 2017

Last Update

November 6 2017

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