Status:

COMPLETED

Prematurity Related Ventilatory Control (PRE-VENT) - Specific Aim 3

Lead Sponsor:

University of Alabama at Birmingham

Conditions:

Infant,Premature

Eligibility:

All Genders

1-98 years

Phase:

NA

Brief Summary

To determine if servo-controlled oxygen environment is associated with reduction in (a) bradycardia events, (b) hypoxemic time, (c) bradycardia time, (d) apneic episodes

Detailed Description

This study will enroll the subset of infants enrolled in the main study (PreVENT Aim 1; 401-1000g at birth and/or 22w 0d-28w 6d; enrolled at \<1 week postnatal age; eligible for full care and survivin...

Eligibility Criteria

Inclusion

  • \- Inborn infants weighing 401-1,000 grams on admission and/or 22w 0/7d to 28w 6/7d (\<29 weeks) inclusive completed weeks of gestation
  • Infants eligible for full care and resuscitation as necessary, and surviving beyond 24 h of age
  • Enrollment in main study protocol (Aim 1 of PreVENT Apnea) at \<1 week post-natal age
  • This study will enroll the subset of infants from Aim 1 who are receiving oxygen supplementation at 32w and 36w PMA, and are not judged too unstable by the Attending neonatologist
  • Informed consent from parent/guardian

Exclusion

  • \- Refusal or withdrawal of consent Major congenital malformations (e.g., not including patent ductus arteriosus, small hernia)

Key Trial Info

Start Date :

April 9 2018

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 1 2021

Estimated Enrollment :

25 Patients enrolled

Trial Details

Trial ID

NCT03333174

Start Date

April 9 2018

End Date

July 1 2021

Last Update

September 21 2021

Active Locations (1)

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1

Regional Neonatal ICU and CCN, University of Alabama at Birmingham

Birmingham, Alabama, United States, 35233