Status:
COMPLETED
Nebulized Heparin and Salbutamol in Mechanically Ventilated Patients With AECOPD
Lead Sponsor:
Ain Shams University
Conditions:
Mechanically Ventilated Patients
Eligibility:
All Genders
18-70 years
Phase:
PHASE4
Brief Summary
This randomised study was designed to assess the efficacy of nebulised heparin and salbutamol in improving lung function in mechanically ventilated patients with AECOPD.
Detailed Description
Methods: Patients: This study was performed between February 2017 and September 2017. Admitted Patients to the Internal Medicine ICU of Ain-Shams University Hospitals were screened for meeting enrol...
Eligibility Criteria
Inclusion
- \> or = 18 years of age,
- body weight 70-110Kg,
- height 160-180 cm
- with clinically evident AECOPD and in need for mechanical ventilation confirmed by arterial blood gases (ABGs).
Exclusion
- Excluded Patients from the study were those who were not enrolled within the first 24 hours of mechanical ventilation and those who were likely to be extubated within 24 hours. - History of ischemic heart disease,
- History of pulmonary bleeding within the previous 3 months,
- History of bleeding diathesis,
- Known to be allergic to heparin or
- History of thrombocytopenia after previous treatment with heparin.
- Female patients were excluded if they were pregnant or breast feeding.
Key Trial Info
Start Date :
February 1 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 30 2017
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT03333395
Start Date
February 1 2017
End Date
September 30 2017
Last Update
July 21 2023
Active Locations (1)
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1
Internal Medicine ICU of Ain-Shams University Hospitals
Cairo, Egypt