Status:
COMPLETED
Gabapentin Regimens and Their Effects on Opioid Consumption
Lead Sponsor:
Brigham and Women's Hospital
Conditions:
Knee Osteoarthritis
Knee Pain Chronic
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
The purpose of this study is to determine the best strategy of administering gabapentin in connection with our current approach to perioperative pain management. We aim to evaluate two different adjun...
Detailed Description
The purpose of this study is to determine the best strategy of administering gabapentin in connection with our current approach to perioperative pain management. We aim to evaluate two different adjun...
Eligibility Criteria
Inclusion
- At least 18 years of age
- Receiving surgery for total knee replacement (TKR)
- Opioid naïve
- Agrees to use tracking diary to monitor opioid consumption
Exclusion
- Over 75 years of age on the date of surgery
- If female, pregnant
- Has received investigational articles \< 30 days prior to enrollment or is currently receiving investigational products or devices
- Chronic pain syndrome
- Taking chronic narcotics and/or taking more than 10 mg of codeine per day, any amount of Hydrocodone, over 200 mg of tramadol per day, or any other narcotics prescribed for moderate or severe pain
- Involved in pain clinics for chronic pain, or pain that is not related to the surgical site
- On long-term gabapentin regimen
- Taking Lyrica or Gralise
- Known history of depression or has been treated for depression with medication
- Has entertained suicidal thoughts and behaviors
Key Trial Info
Start Date :
May 15 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 24 2019
Estimated Enrollment :
77 Patients enrolled
Trial Details
Trial ID
NCT03334903
Start Date
May 15 2018
End Date
April 24 2019
Last Update
February 18 2021
Active Locations (1)
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1
Brigham and Women's Faulkner Hospital
Boston, Massachusetts, United States, 02130