Status:

UNKNOWN

Cognitive Remediation in Alcohol Disorders

Lead Sponsor:

University Hospital, Caen

Conditions:

Alcohol Disorders

Eligibility:

All Genders

18-60 years

Phase:

NA

Brief Summary

The individual and societal cost of alcohol use disorders (TUAL), present in 10% of the population in France, is considerable. Despite psychotherapeutic and drug addiction treatment, the relapse rate ...

Eligibility Criteria

Inclusion

  • Patient male or female aged 18 to 60, French speaking and affiliated to the social security system
  • Patient with TUAL (DSM-5) at the forefront of alcohol use disorders at the time of inclusion
  • Patient with neuropsychological disorders objectified on BEARNI (BEARNI for Brief Evaluation of Alcohol-Related Neuropsychological Evaluation, Ritz et al., 2015 cut-off cognitive score = 13, adding a point for patients with bachelor level or lower) and confirmed at the neuropsychological checkup showing pathological performance (at least two free or total recalls of RL / RI 16 \<-1.65 and / or RBMT IGM \<-1.65 OR number of persecutory or deficit errors at MCST \<-1.65 and / or at least two BADS subtests with a score of \<or = 2 (except temporal judgment)). Evaluation (BEARNI) at least 48h after stopping benzodiazepines
  • Patient weaned of alcohol, that is to say between 5 and 21 days after stopping alcohol, after disappearing signs of withdrawal (Cushman score \<2) and stopping benzodiazepines
  • First hospitalization type day hospital (not necessarily first weaning)
  • Patient having been informed of the study and being able to give written informed consent.

Exclusion

  • Patient with severe and long-lasting neurological complications related to alcohol (Korsakoff syndrome, fetal alcohol syndrome, ...)
  • Patient with a disorder of severe use of another psychoactive substance according to DSM-5, except tobacco
  • Patient with motor or sensory deficit making cognitive remediation impossible
  • Patient previously included or already included in another biomedical research
  • Homeless patient

Key Trial Info

Start Date :

February 1 2018

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

February 1 2020

Estimated Enrollment :

150 Patients enrolled

Trial Details

Trial ID

NCT03335215

Start Date

February 1 2018

End Date

February 1 2020

Last Update

November 7 2017

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Cognitive Remediation in Alcohol Disorders | DecenTrialz