Status:

COMPLETED

GALNT4 in Patients With Acute Coronary Syndrome

Lead Sponsor:

The First Affiliated Hospital of Dalian Medical University

Conditions:

Acute Coronary Syndrome

Eligibility:

All Genders

18-80 years

Brief Summary

The expression of GALNT4 in blood with acute coronary syndrome

Detailed Description

Emerging evidences have linked GALNTs to cardiovascular disease or susceptibility to CAD.GALNT4, a member of the GalNAc-Ts family,contributes to the initiation of O-linked. Polymorphisms in GALNT4 hav...

Eligibility Criteria

Inclusion

  • diagnosed as acute coronary syndrome,including STEMI,NSTE-ACS,or diagnosed as SAP by CAG.
  • with left ventricular ejection fraction(LVEF)\>=45%
  • written informed consents are obtained
  • admitted within 24 hours after chest pain attacked(except SAP)

Exclusion

  • • complicated with rheumatic heart disease, coronary arteritis, hypertrophic cardiomyopathy or dilated cardiomyopathy
  • complicated with malignant tumor,the immune system diseases, blood system diseases, recently (within 2 weeks) taking glucocorticoid drugs, the use of immunosuppressive agents and cerebral infarction
  • with acute or chronic infection, surgery or trauma in the last month
  • secondary hypertension, severe liver dysfunction,severe renal insufficiency
  • with abnormal thyroid function or allergy to iodine agent
  • refusal to sign the informed consent

Key Trial Info

Start Date :

September 1 2017

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

December 31 2018

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT03335514

Start Date

September 1 2017

End Date

December 31 2018

Last Update

March 19 2019

Active Locations (1)

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The First Affiliated Hospital of Dalian Medical University

Dalian, Liaoning, China, 116011