Status:
COMPLETED
The Effect of Propofol or Sevoflurane on Renal Function
Lead Sponsor:
Uppsala University
Collaborating Sponsors:
The Swedish Research Council
Conditions:
Acute Kidney Injury
Anesthesia
Eligibility:
All Genders
18-65 years
Phase:
PHASE4
Brief Summary
This study investigates the role of the anesthetic agents propofol and sevoflurane on renal function in otherwise healthy patients undergoing basic back surgery.
Detailed Description
Water-sodium homeostasis is central for anyone undergoing surgery, and can therefore affect surgical outcome, level of postoperative care and the length of hospital stay. Too much or too little fluid ...
Eligibility Criteria
Inclusion
- Scheduled back surgery
Exclusion
- American Association of Anesthesiology class 1-3
- American Heart Association class \>3
- BMI \>37
- Insulin treated diabetes
- Pregnancy or breast feeding
- Sensistivity/allergy against anesthetic agents
- Inadequate understanding about the study
- Depressed kidney function and/or AKI
- Depressed liver function
- Genetic malignant hyperthermia
Key Trial Info
Start Date :
September 1 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 10 2020
Estimated Enrollment :
37 Patients enrolled
Trial Details
Trial ID
NCT03336801
Start Date
September 1 2017
End Date
January 10 2020
Last Update
April 2 2021
Active Locations (1)
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1
Akademiska sjukhuset, Centraloperation
Uppsala, Sweden, 75185