Status:
ACTIVE_NOT_RECRUITING
PRecISion Medicine for Children With Cancer
Lead Sponsor:
Sydney Children's Hospitals Network
Collaborating Sponsors:
Children's Cancer Institute Australia
Australian & New Zealand Children's Haematology/Oncology Group
Conditions:
Childhood Cancer
Childhood Solid Tumor
Eligibility:
All Genders
Up to 21 years
Brief Summary
This is a multicentre prospective study of the feasibility and clinical value of a diagnostic service for identifying therapeutic targets and recommending personalised treatment for children and adole...
Detailed Description
This is a multicentre study conducted under the Zero Childhood Cancer Program. The study will be enrolling patients under the age of 21 with high-risk cancer over 3 years from cancer centres in Austra...
Eligibility Criteria
Inclusion
- Inclusion criteria (all must be met)
- Age ≤ 21 years
- Histologic diagnosis of high-risk malignancy defined as expected overall survival \< 30% OR where standard therapy would result in unacceptable and severe morbidity
- Appropriate tissue samples are available for analysis
- Life expectancy \> 6 weeks
- Written informed consent
Exclusion
Key Trial Info
Start Date :
September 5 2017
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2032
Estimated Enrollment :
550 Patients enrolled
Trial Details
Trial ID
NCT03336931
Start Date
September 5 2017
End Date
December 1 2032
Last Update
April 23 2024
Active Locations (8)
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1
John Hunter Children's Hospital
Newcastle, New South Wales, Australia, 2305
2
Sydney Children's Hospital, Randwick
Sydney, New South Wales, Australia, 2031
3
The Children's Hospital at Westmead
Sydney, New South Wales, Australia, 2145
4
Queensland Children's Hospital
Brisbane, Queensland, Australia, 4101