Status:

COMPLETED

The Impact of Co-Dispensing Naloxone to Patients Prescribed Chronic Opioid Therapy

Lead Sponsor:

Kaiser Permanente

Collaborating Sponsors:

Denver Health and Hospital Authority

National Institute on Drug Abuse (NIDA)

Conditions:

Overdose

Risk Behavior

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

In the setting of naloxone standing orders, this study will assess if co-dispensing naloxone with opioids to patients prescribed chronic opioid therapy changes opioid risk behaviors, increases naloxon...

Detailed Description

This is a pragmatic, pharmacy-based, cluster randomized controlled trial of a naloxone co-dispensing program for adults prescribed chronic opioid therapy. Pharmacies (target N=6) will be randomized to...

Eligibility Criteria

Inclusion

  • Study Population:
  • Eligible pharmacies
  • Patients prescribed chronic opioid therapy
  • Inclusion Criteria for pharmacies:
  • Stock naloxone for outpatient dispensing.
  • Pharmacy leadership willing to provide naloxone under a co-dispensing protocol.
  • Pharmacy leadership willing to be randomized to order of implementation.
  • Have or can implement a naloxone standing order.
  • Exclusion Criteria for pharmacies:
  • • None
  • Inclusion Criteria for patients:
  • Prescribed chronic opioid therapy and meet criteria for the pharmacy co-dispensing protocol
  • Receive medications at participating pharmacies
  • Have a health plan which covers the formulation of naloxone available at the pharmacy they received their opioid prescriptions from.
  • (for surveys)18 years of age or greater
  • Exclusion Criteria:
  • • (for surveys) Non-English speaking, hospice enrollment, do-not-resuscitate order

Exclusion

    Key Trial Info

    Start Date :

    November 27 2017

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    September 30 2022

    Estimated Enrollment :

    7 Patients enrolled

    Trial Details

    Trial ID

    NCT03337100

    Start Date

    November 27 2017

    End Date

    September 30 2022

    Last Update

    March 3 2023

    Active Locations (1)

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    Denver Health

    Denver, Colorado, United States, 80204