Status:

UNKNOWN

Pharmacodynamics and Pharmacokinetics of Dexmedetomidine in Pediatric

Lead Sponsor:

Chinese Medical Association

Conditions:

Pediatrics

Dexmedetomidine

Eligibility:

All Genders

3-9 years

Phase:

PHASE4

Brief Summary

1. Acute Hemodynamic and respiratory Changes After Rapid Intravenous different doses of Dexmedetomidine in Pediatric. 2. Pharmacokinetics after a single Rapid Intravenous dose of Dexmedetomidine in Pe...

Eligibility Criteria

Inclusion

  • selective operation of inguinal hernia repair、orthopedics operation or general surgery operation in children
  • aged 3-9 years
  • ASA I - II
  • enter the operating room by himself without parents
  • normal liver and kidney function
  • no history of anesthesia medication allergy.

Exclusion

  • allergic to dexmedetomidine, similar active ingredients or excipients
  • G-6-PD deficiency
  • a history of arrhythmia, bronchial and cardiovascular diseases, abnormal liver function and so on
  • a history of use of alpha 2 receptor agonists or antagonists.

Key Trial Info

Start Date :

October 20 2017

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

July 1 2019

Estimated Enrollment :

187 Patients enrolled

Trial Details

Trial ID

NCT03337581

Start Date

October 20 2017

End Date

July 1 2019

Last Update

November 9 2017

Active Locations (1)

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The second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University

Wenzhou, Zhejiang, China, 325027