Status:

UNKNOWN

Analysis With Clusters of QUAntitative Tomodensitometric Vascular, bronchIal and Parenchymal Pulmonary Parameters for COPD Patients

Lead Sponsor:

University Hospital, Bordeaux

Collaborating Sponsors:

Transitionnal Research International Laboratory

Conditions:

Chronic Obstructive Pulmonary Disease

Eligibility:

All Genders

40+ years

Brief Summary

Chronic obstructive pulmonary disease (COPD) is caused by tobacco consumption. The goal is to characterize on clinical and radiological data, using computed tomography, this illness in order to improv...

Detailed Description

Chronic obstructive pulmonary disease (COPD) is characterized by emphysematous destruction of pulmonary parenchyma, airway obstruction that participate in chronic temporary obstruction of airways. COP...

Eligibility Criteria

Inclusion

  • Age ≥ 40 years
  • Inhalated toxic exposure:
  • Tobacco exposure (present or past, over 10 pack years)
  • And/or professional exposure to a toxic
  • Obstructive syndrome with a FEV1/FVC ≤ 0.7 after inhalation of a bronchodilatator and measured at stable state (without exacerbation)
  • Computed tomography performed without injection contrast during common care

Exclusion

  • Patients with an exacerbation within 6 weeks before computed tomography
  • Artefacts movements on computed tomography incompatible with quantitative analyse
  • Broncho-pulmonary cancer (old or present)
  • History of pulmonary surgery
  • No follow-up for 1 year after scan
  • Opposition of the patient to the use of his data (clinical, functional and imaging).

Key Trial Info

Start Date :

December 20 2017

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 1 2018

Estimated Enrollment :

270 Patients enrolled

Trial Details

Trial ID

NCT03337854

Start Date

December 20 2017

End Date

December 1 2018

Last Update

November 28 2017

Active Locations (1)

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Centre Hospitalier Universitaire de Bordeaux

Bordeaux, France, 33000