Status:

COMPLETED

Evaluation of Metamemory in Patients With Schizophrenia

Lead Sponsor:

University Hospital, Clermont-Ferrand

Collaborating Sponsors:

LAPSCO, Psychology University, Blaise Pascal University, Clermont-Ferrand.

Conditions:

Schizophrenia

Aging

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The purpose of this study is to determine the respective roles of aging and schizophrenia in the regulation of metamemory using a generation strategy. 4 groups will be necessary to comparison: Adult ...

Detailed Description

Metamemory measurement * Objective: Measurement of monitoring and control capabilities, and relations between these two abilities when learning of word pairs. * Description: The hardware consists of ...

Eligibility Criteria

Inclusion

  • For both:
  • Age: between 18 and 45 years for adults, and 59.55 and above for older,
  • For patients :
  • DSM-5 criteria of schizophrenia
  • Adult patients (\<45 years) will be matched to elderly patients (\> 59.55 years) gender and educational level,
  • Patients followed as outpatients,
  • Age of onset of the disease less than 40 years,
  • Patients whose disease has stabilized: no changes psychotropic treatment for at least 1 month
  • Not more of a benzodiazepine,
  • Patients on protection of justice or not,
  • For controls :
  • \- Matched for sex to patient
  • Age-matched (+/- 3 years) to patient
  • Matched for educational level (+/- 2 years) to patients

Exclusion

  • -For patients :
  • Any other comorbid psychiatric diagnosis of Axis I DSM-5 (particularly depression, addiction excluding tobacco, dementia)
  • Patients with impaired vision or hearing preventing the realization of the tests.
  • Long-term Anticholinergic treatment.
  • Patients with less 5 years of school
  • For controls:
  • Any psychiatric diagnosis according to DSM-5, including addictions (excluding tobacco)
  • Head injuries, brain injuries or diseases,
  • vision or hearing problems preventing the realization of the tests.
  • Current or past addiction to all toxic substances except tobacco.
  • Long-term Anticholinergic treatment.
  • Related to the first degree diagnosed with a psychotic disorder

Key Trial Info

Start Date :

February 8 2011

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 23 2016

Estimated Enrollment :

120 Patients enrolled

Trial Details

Trial ID

NCT03338179

Start Date

February 8 2011

End Date

May 23 2016

Last Update

November 14 2017

Active Locations (1)

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CHU Clermont-Ferrand

Clermont-Ferrand, France, 63003