Status:
COMPLETED
Determining the Mechanism of Myocardial Injury and Role of Coronary Disease in Type 2 Myocardial Infarction
Lead Sponsor:
University of Edinburgh
Collaborating Sponsors:
British Heart Foundation
Conditions:
Myocardial Infarction, Acute
Myocardial Ischemia
Eligibility:
All Genders
Brief Summary
Myocardial injury is common in patients without acute coronary syndrome, and therefore international guidelines propose a classification of patients with myocardial infarction by aetiology. This diffe...
Detailed Description
The investigators will systematically evaluate the mechanisms of acute myocardial injury in unselected patients who present to hospital with an alternative primary illness likely to cause myocardial o...
Eligibility Criteria
Inclusion
- Unscheduled hospital admission with acute myocardial injury (defined as a rise and or fall in high-sensitivity cardiac troponin I concentrations on blood testing)
- A suspected aetiology of myocardial oxygen supply and demand imbalance with symptoms or signs of myocardial ischaemia
Exclusion
- Unable or unwilling to give informed consent
- Women who are pregnant, breastfeeding or of child-bearing potential (women who have experienced menarche, are pre-menopausal and have not been sterilised) will not be enrolled into the trial.
- Probable type 1 myocardial infarction
- Renal impairment (estimated glomerular filtration rate ≤30ml/min/1.73m2)
- Severe hepatic impairment
- Frailty with inability to self-transfer (determined using Katz Index)
Key Trial Info
Start Date :
October 23 2017
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
November 6 2021
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT03338504
Start Date
October 23 2017
End Date
November 6 2021
Last Update
June 10 2022
Active Locations (1)
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1
Centre for Cardiovascular Science
Edinburgh, United Kingdom, EH16 4SB