Status:

WITHDRAWN

Procedure RElated Outcomes With the Watchman FLX Left Atrial Appendage Closure Device

Lead Sponsor:

Oxford University Hospitals NHS Trust

Collaborating Sponsors:

Boston Scientific Corporation

Conditions:

Atrial Fibrillation

Stroke

Eligibility:

All Genders

18-100 years

Brief Summary

This study is a single-centre prospective post-market approval of the early experience with the Watchman FLX device for left atrial appendage closure in patients with atrial fibrillation at high risk ...

Detailed Description

Principal study aim: To document the impact of the next generation of Watchman LAAC device on key aspects of the implant procedure Study Rationale: As an interventional procedure it is important that...

Eligibility Criteria

Inclusion

  • Patients who meet current clinical criteria for LAAC, ie have atrial fibrillation, a CHA2DS2-VASc score of 3 or more and a contraindication to long-term oral anticoagulation therapy and who have been approved by the Oxford University Hospitals (OUH) NHS Foundation Trust LAAC MDT as suitable for left atrial appendage occlusion in accordance with NHS guidelines.
  • A subject will be considered for enrolment in the study if all of the following inclusion criteria are met, provided no exclusion criteria are met:
  • Subjects who are eligible for a WATCHMAN FLX device per physician discretion according to current international and local guidelines and currently approved indications
  • Subjects who are willing and capable of providing informed consent and participating in all testing associated with this clinical investigation at an approved clinical investigational centre
  • Subjects whose age is 18 years or above, or of legal age to give informed consent specific to national law.

Exclusion

  • Subjects who are currently enrolled in another investigational study or registry that would directly interfere with the current study, except when the patient is participating in a mandatory governmental registry, or a purely observational registry with no associated treatments.
  • Subjects who are unable or not willing to complete the follow-up visits and examination at 6 weeks.
  • Women of childbearing potential who are, or plan to become, pregnant during the time of the study (method of assessment upon physician's discretion).
  • Documented life expectancy of less than 12 months.

Key Trial Info

Start Date :

January 1 2016

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

June 1 2016

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT03339193

Start Date

January 1 2016

End Date

June 1 2016

Last Update

November 13 2017

Active Locations (1)

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1

Department of Cardiology, John Radcliffe Hospital

Oxford, United Kingdom, OX3 9DU