Status:

TERMINATED

Enhanced Lithotripsy System (ELS) in the Treatment of Urinary Stone Disease

Lead Sponsor:

Avvio Medical

Conditions:

Urinary Stone

Eligibility:

All Genders

18-75 years

Phase:

NA

Brief Summary

This is a single arm, multi-center study to assess the safety and efficacy of a form of extracorporeal lithotripsy, called the Enhanced Lithotripsy System, to treat urinary stones.

Detailed Description

This is a single arm, multi-center study to assess the safety and efficacy of a form of extracorporeal lithotripsy, called the Enhanced Lithotripsy System, to treat urinary stones. Subjects will be tr...

Eligibility Criteria

Inclusion

  • Male or female aged ≥ 18 years to ≤ 75 years.
  • One urinary stone-apparent on a computed tomography (CT) scan within 14 days prior to study enrollment
  • Stone size, as estimated by pre-procedure CT, with all dimensions 15 mm or less.
  • Provides written informed consent
  • Understands and accepts the study requirements

Exclusion

  • Age less than 18 years of age or over 75 years of age
  • Diagnosis of radiolucent stones
  • Diagnosis of stones in the lower pole of kidney
  • History of cystinuria
  • Urine pH below 5.5
  • Current untreated urinary tract infection
  • Pregnancy
  • Coagulation abnormality or taking prescription anticoagulants. Aspirin usage will be discontinued at least 7 days prior to enrollment at the discretion of the attending physician.
  • Mobility issues - unable to comfortably lie still for up to 30 minutes or unable to roll from back to side
  • Known hypersensitivity to conductivity gel
  • Vulnerable individuals (mentally disabled, physically disabled, prisoner, etc.)
  • Body mass index greater than 35
  • American Society of Anesthesiologists (ASA) score of 3 or greater general anesthesia risk level
  • Known sensitivity to possible medications used before, during, or after the ELS procedure, including but not limited to the following: sedative agents, general anaesthetics, topical anaesthetics, and opioid analgesics.
  • Enrollment in another research study or previous participation within 30 days of enrollment.

Key Trial Info

Start Date :

December 8 2017

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 5 2022

Estimated Enrollment :

13 Patients enrolled

Trial Details

Trial ID

NCT03339388

Start Date

December 8 2017

End Date

October 5 2022

Last Update

April 17 2024

Active Locations (4)

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Page 1 of 1 (4 locations)

1

McArthur Urology

Campbelltown, New South Wales, Australia, 2560

2

Westmead Private Hospital

Westmead, New South Wales, Australia, 2145

3

Goldfields Urology

Bendigo, Victoria, Australia, 3550

4

Austin Health

Melbourne, Victoria, Australia, 3084